Our work focusses on improving diagnostics, treatment, and prevention strategies to combat this global health challenge. Below are the key areas of TB research at the IDM:

Diagnosis, Pathogenesis & Management of TB, TB-IRIS & TBM

Understanding the mechanisms of TB infection, including immune responses and disease progression, is essential for better patient outcomes. Our research explores:

  • Improved diagnostic techniques for early and accurate TB detection.

  • The pathogenesis of TB, with a focus on immune responses and inflammatory complications such as TB Immune Reconstitution Inflammatory Syndrome (TB-IRIS) and Tuberculous Meningitis (TBM).

  • Innovative approaches for managing TB and its complications.

Biomarker Discovery

Identifying reliable biomarkers is crucial for TB diagnosis, treatment monitoring, and prognosis. Our research focusses on:

  • Finding molecular and immunological markers for early TB detection.

  • Biomarkers that predict treatment response and disease progression.

  • Developing non-invasive diagnostic tests using biomarker technology.

Vaccine Development

Preventing TB through effective vaccination is a key priority. Our scientists are engaged in:

  • Developing next-generation TB vaccines with enhanced efficacy.

  • Conducting clinical trials to evaluate new vaccine candidates.

  • Studying immune responses to improve vaccine design.

Aerobiology

Understanding how TB spreads through the air is critical for infection control. Our aerobiology research includes:

  • Studying airborne transmission dynamics in different environments.

  • Evaluating air filtration and ventilation strategies to reduce TB spread.

Latest TB news from the IDM

TB day 2025

The IDM’s Contribution Towards Ending Tuberculosis: Commit, Invest, Deliver