IDM CPD-Accredited Seminar: Histology Core Facility Showcase

Dr Darby has spent the bulk of his career at UCT investigating novel insights into host immunity to parasitic helminth infection. He has demonstrated that B cells are able to rapidly activate T cells to confer protection against infection with the helminth Nippostrongylus brasiliensis (Horsnell, Darby et al., PLoS Pathogens 2013) and built on this to show a mother transferred cellular immunity to offspring via T cell transfer in breast milk (Darby, Chetty et al., Science Advances 2019).

Dr Darby did his postdoctoral research showing ILC3 ACh-mediated allergic inflammation in the Lung (Darby et al., JACI 2021). These findings increase our understanding of an important cause of type 2 immunity, helminth infection, and of pulmonary immunity in general.Dr Darby now manages the IDM Histology Core Facility at UCT, where histology samples are processed and stained to researchers’ requirements.