Dr. Erin McCaffrey received her PhD in Immunology with a specific focus on Computational & Systems Immunology at Stanford University as an NSF Graduate Research Fellow. She conducted her thesis work under Dr. Michael Angelo where she employed newly developed, highly multiplexed tissue imaging to generate the first spatial single-cell atlas of human tuberculosis (TB) granulomas.

Dr. McCaffrey then worked as a postdoctoral fellow at Stanford University with Dr. Mark Davis and as a visiting fellow at the Swiss Tropical & Public Health Institute with Dr. Damien Portevin. During this time, she worked on leveraging in vitro organoid systems to model TB immunopathogenesis in granulomas and lymphoid tissues.

Dr. McCaffrey joined the NIH as an Independent Research Scholar in 2023 where she leads the Spatial Immunology Unit. Her lab integrates tissue mapping approaches and human-based in vitro models to define the principles of immune programming in tissues during infection and chronic inflammation with a primary focus on tuberculosis