IDM CPD-Accredited Seminar: Statins as Host-Directed Drug Therapy for Tuberculosis
Times
Wed, 26 Nov 25
13:00 - 14:00
Speaker
Prof Reto Guler
Div. of Immunology
Host
Prof Suraj Parihar
Div. of Medical Microbiology
IDM CPD-Accredited Seminar Program 2025
26 November 2025 | 13:00 - 14:00
Wolfson Pavilion Lecture Theatre, IDM Building
Speaker
Reto Guler is a Full Professor in the Division of Immunology and the Institute of Infectious Disease & Molecular Medicine. His research focuses on identifying host factors and pathways exploited by Mycobacterium tuberculosis to enhance its persistence within macrophages, with the goal of developing both pathogen- and host-directed therapies for tuberculosis (TB). His work includes investigating statins, non-coding RNAs, and the role of epigenetics in host immunity to TB. He coordinates the international Statin-TB consortium, funded by the European & Developing Countries Clinical Trials Partnership, which is evaluating statins in a clinical trial to reduce post-TB lung disease. Guler is also a member of the international FANTOM consortium, which advances genome-wide transcriptome analysis through CAGE transcriptomics (Nature, 2014; Science, 2015). Additionally, his research explores Minor Groove Binders as innovative anti-mycobacterial agents and investigates non-ionic surfactant vesicles as drug delivery systems for TB. His work exemplifies the translation of fundamental research into clinical applications to identify novel treatments for TB.