Dr Pauline van der Watt

Research Officer

Affiliations

  1. Research Fellow, Institute of Infectious Disease and Molecular Medicine
  2. Centre for developing cancer therapeutics for Africa (CDCTA)
  3. Medical Biotechnology and Immunotherapy Research Unit (MB&I)

Key Expertise

Biomarker Discovery, Cancer (Prevalent), Cervical Cancer, Drug Discovery, Molecular Medicine

Main Research Focus

Pauline’s research focuses on investigating the link between the circadian clock and cancer, at the molecular level. An improved understanding of how the circadian clock is altered in cancer cells can impact chronotherapy (the timing of administration of chemotherapy), improving the efficacy of current chemotherapies. Additionally, targeting the circadian clock with small molecules can have an anti-tumourigenic effect. Other research interests include investigating the nuclear transport proteins in cancer and their potential as diagnostic and therapeutic markers.